This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

In contemporary organizations, it is common to encounter teams that are formed to create novel outcomes and that are supported by Information Communication Technologies (ICT). These knowledge teams are also formed by members with diverse expertise, in order to create…

Reference documentation is an important source of information on API usage. Programmers, however, can easily overlook reference information because of its tedious nature, and because the information they seek can be buried among irrelevant or boiler-plate text. We propose to…

Knowledge translation (KT) has been referred to as "the methods for closing the gaps from knowledge to practice" (Straus, Tetroe & Graham, 2009). During the 2010-2011 academic year, a research project was conducted in the three high schools of the…

This thesis examines the production and mobilization of Inuit knowledge in and beyond the Canadian Arctic in the context of climate change. Drawing on multi-scale, ethnographic research, it focuses in particular on the role of institutions, such as government departments…

This thesis examines variation in the practices of al-Qaeda and the American counterterrorism community. It posits that the interaction of two permissive factors, background knowledge and relational structure, goes a long way in explaining shifts in the practices of both…

The promotion of stakeholders' dialogue and knowledge management at the local level has been heralded by academic researchers as an approach with the potential to address the global challenge of inadequate potable water delivery. However the current design and execution…

This thesis examined bilingual reading comprehension within the parameters of two theories of second language (L2) reading comprehension performance: the Linguistic Interdependence Hypothesis (LIH) and the Linguistic Threshold Hypothesis (LTH). The oral language skills and metacognitive knowledge and reading strategies…