Aggressive epithelial cancer cells frequentlyadopt mesenchymal characteristics and exhibitaberrant interactions with their surroundings,including the vasculature. Whether therelease/uptake of extracellular vesicles (EVs)plays a role during these processes has not beenstudied. EVs are heterogeneous membranestructures that originate either at the surface(microparticles), or…

This study explored the information needs of rehabilitation therapists (occupational therapists, physiotherapists and speech-language pathologists) working with patients with stroke, to characterize their clinical questions, that is, their formalized information needs. This study also investigated how rehabilitation therapists decide whether…

Objective: Despite the established effectiveness of medication in improving symptoms of attention-deficit hyperactivity disorder (ADHD) (Spencer et al 2000), rates of adherence to pharmacotherapy are low, ranging from 34% to 91% (Gau et al., 2006). Since higher adherence rates are…

This dissertation explores the socio-cultural implications of content and context in Vygotsky's theory of the private speech of young children (Vygotsky, 1986). While private speech has long been thought to hold a snapshot of the child in cognitive transition, the…

Invasive research procedures, such as biopsy for pharmacodynamic study, often have no value for patient-volunteers in terms of diagnosis or clinical management. Accordingly, their burdens are generally justifiable only by appeal to knowledge value (that is, the benefit to future…

With the current issue of Evidence Based Libraryand Information Practice (EBLIP), we will havepublished over 250 evidence summaries.That’s an average of 8 per issue, or 32 per year.When the journal was created, the goal ofpublishing these summaries was to provideconcise…