Many children misarticulate more sounds than expected for their age and present with a Developmental Phonological Disorder (DPD). Children with DPD are at risk for later academic and socio-emotional difficulties. Successful intervention for these children is dependent on a good…

While bereavement interventions have proved effective in reducing complicated/prolonged grief reactions, the scholarship over the past 10 years suggests that the effectiveness of bereavement interventions for uncomplicated grief is negligible. However, these past studies have been critiqued for numerous design…

Opioid and α2-adrenergic receptor (α2AR) ligands are both analgesic when administered spinally and show a clinically beneficial synergistic interaction in the treatment of pain when co-administered. The µ- and δ-opioid receptors (MOR and DOR respectively) and the α2AARs have been…

The lack of information about the interaction of metal mixtures in soils encouraged us to improve the knowledge on the toxicity of mixtures of copper (Cu), nickel (Ni), and zinc (Zn). Risk assessors estimate the concentration of trace metals that…

Background: Annually, an estimated 8.2% of Canadians aged 18 or older are affected by major depressive disorder (MDD). Nearly half of those suffering from MDD will fail to achieve remission while also having an inadequate response to an initial and…

Macromolecular drug delivery systems, or nanocarriers, designed to improve the bioavailability of therapeutic and diagnostic agents, are promising tools for the site-specific delivery of drugs to the central nervous system (CNS). In particular, nanocarriers exhibit inherent activity that can be…

Uveal Melanoma (UM) is the most common intraocular tumor in adults. Liver metastasis is the leading cause of death in patients affected by this disease and in approximately 40% of the cases, metastasis occurs 10 years after initial diagnosis. Tumor…

Ultra Wideband (UWB) Impulse Radio (IR) technology has attracted considerable attention in the past few years due to its many desirable properties, such as the ability to penetrate through walls and ground, low power spectral density level, immunity to multipath…

Introduction: Current epidemiological evidence suggests that asthma and allergic conditions have an etiological component rooted in prenatal development. One of the associated risk factors is the exposure of the conceptus to prenatal maternal stress (PNMS). Current information on the effects…

Non-suicidal self-injury (NSSI) is defined as the deliberate destruction of one's own body tissue without suicidal intent and for purposes not socially sanctioned, thus excluding tattooing and piercing (Favazza, 1998). The high prevalence rate in both clinical and community studies…