This thesis presents a methodology for prediction of reliability for a lunar rover and a technique to evaluate reliability where data for operation in the lunar environment are not available in order to conduct traditional reliability analysis. This technique was…

Early studies of antidepressants have demonstrated clinical efficacy at doses much lower than those currently recommended. Even when deemed sub-therapeutic by modern standards, lower doses are often clinically effective – perhaps through a placebo effect. Emerging from clinical trial analyses,…

Activins are members of the transforming growth factor β (TGFβ) superfamily. Though originally identified as stimulators of pituitary follicle-stimulating hormone (FSH) synthesis and secretion, they also play diverse biological roles, ranging from control of cellular differentiation to regulation of immune…

Impulsivity is considered a major contributor to various antisocial behaviours (Nofziger, 2010) and is present in many mental and personality disorders (American Psychiatric Association, 2000). Given that clear sex differences have been observed in such behaviours and disorders (Nofziger, 2010;…

Breast cancer is the most frequently diagnosed and the second leading cause of cancer deaths in Canadian women. The most devastating and deadly feature of the disease is the emergence of metastases. Breast cancer most commonly metastasizes to bone, often…

Modern agriculture has led to fundamental changes in the phosphorus (P) cycle that pose agronomic and environmental challenges at all scales. Phosphorus is a non-renewable resource that is critical to food production because of its role as an essential plant…

This qualitative study explored the educational and occupational decisions of emerging adults from a small Caribbean island (referred to as "SCI") during a time of robust socioeconomic and infrastructure development, followed by a sudden change in the labor market resulting…

Heat shock cognate 70 kDa protein (hsc70) is a well conserved molecular chaperone involved in many physiological functions such as the stress response, protein folding, and protein transport. Moreover, hsc70 plays roles in human disease, such as cancer, neurodegenerative disease,…

This thesis focuses on Mean Field Game (MFG) theory with applications to consensus, flocking, leader-follower and major-minor agent systems. The MFG methodology addresses a class of dynamic games with a large number of minor agents in which each agent interacts…

Collaborative information behaviour is an emerging area in information science that deals with the identification, seeking, searching, and use of information by two or more people to accomplish a task. This dissertation investigates the collaborative information behaviour of senior undergraduate…