This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

Concept maps are graphical representations of relationships among concepts that can be an effective tool for teaching, designing, and organizing information in a variety of library settings. Concept maps can be used wherever training or formal teaching occurs as a…

This essay illuminates the historical context of the contemporary language of globalization. It argues that the key concepts of the “global” began in ancient Greek thought about unseen space, before being reified through the Renaissance invention of the terrestrial globe.…

With the increasing demand for composite materials by the industry, the adhesive joints emer ge as an attractive alternative to traditional mechanical joints. The latter require as a preliminary step, the drilling of the laminates with consequent damage to the…

This dissertation sets out to examine the conceptual domains of CHANGE and
POSSESSION by selecting two main verbal classes, namely entity-specific change-ofstate verbs for the domain of CHANGE and contribute verbs for that of POSSESSION.
The most important step consisted…

In June 2008, the Brazilian Interdisciplinary AIDS Association (ABIA) and the Indian NGO SAHARA submitted a joint pre-grant opposition to the patent application of Tenofovir Disoproxil Fumarate in India. This joint action provides a pertinent case model of the potential…

Potato is an important staple food and horticultural crop for Argentina and it is included in almost every meal prepared by households. The annual average per capita consumption of potatoes is 40 kg. Despite the rapid rise of supermarkets, small…

CMOS IC scaling has provided significant improvements in electronic circuit performance.
Advances in test methodologies to deal with new failure mechanisms and nanometer issues
are required. Interconnect opens are an important defect mechanism that requires detailed
knowledge of its physical…