Many asymptotic results for kernel-based estimators were established under some smoothness assumption on density. For cases where smoothness assumptions that are used to derive unbiasedness or asymptotic rate may not hold we propose a combined estimator that could lead to…

I consider the implementation problem under complete information and employ Nash equilibrium as a solution concept. A socially desirable rule is given as a correspondence from the set of states to the set of outcomes. This social choice rule is…

I consider a strategic game form with a finite set of payoff states and employ undominated Nash equilibrium (UNE) as a solution concept under complete information. I propose notions of the proximity of information according to which the continuity of…

BACKGROUND:A variety of definitions of evidence-based practice (EBP) exist. However, definitions are in themselves insufficient to explain the underlying processes of EBP and to differentiate between an evidence-based process and evidence-based outcome. There is a need for a clear statement…

BACKGROUND:Primary prevention of breast cancer through prophylactic mastectomy can reduce the risk of malignancy in high-risk individuals. No type of mastectomy completely removes all breast tissue, but a subcutaneous mastectomy leaves more tissue in situ than does a simple mastectomy.CASE…

Good command of anatomy is a basic requirement for studying and practicing clinical disciplines. A common difficulty that faces many medical and dental students (at least this was the case with the author) is how to keep their knowledge of…

This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

We found the linear complexity of quaternary sequences of period over the ring Z_4 . The sequences are based on Whiteman's generalized cyclotomic classes of order four. Also we derived the maximum nontrivial autocorrelation magnitude of the constructed sequences.