| Título: | Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature |
| Autores: |
Kasprzak, Lidia Mesurolle, Benoit Tremblay, Francine Galvez, Maria Halwani, Fawaz Foulkes, William |
| Fecha: |
2005 2006-05-06 |
| Publicador: | McGill University - MCGILL |
| Fuente: |
 |
| Tipo: | article |
| Tema: | |
| Descripción: | BACKGROUND:Primary prevention of breast cancer through prophylactic mastectomy can reduce the risk of malignancy in high-risk individuals. No type of mastectomy completely removes all breast tissue, but a subcutaneous mastectomy leaves more tissue in situ than does a simple mastectomy.CASE PRESENTATION:We report a case of invasive breast cancer in a BRCA2-positive woman 33 years after bilateral subcutaneous mastectomy. To our knowledge, only one case of primary breast cancer after prophylactic mastectomy in a BRCA1-positive patient has been reported in the literature and none in BRCA2-positive individuals.CONCLUSION:Careful documentation and long follow-up is essential to fully assess the benefits and risks of preventive surgical procedures in BRCA1 and BRCA2 mutation carriers. |
| Idioma: | eng |
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