| Título: | Serum Aspartate Transamınase is not a Useful Diagnostic Biomarker in Industrial Toluene Exposure |
| Autores: |
Tutkun, Engin; Department of Occupational Toxicology, Occupational Diseases Hospital, 06200 Ankara, TURKEY Abuşoğlu, Sedat; Department of Biochemistry, Selcuk University Faculty of Medicine, 42200 Konya, Turkey Yılmaz, Hınç; Department of Occupational Toxicology, Occupational Diseases Hospital, 06200 Ankara, TURKEY Bacaksız, Ayşegül; Department of Nutrition Health, Hacettepe University Faculty of Medicine, 06200 Ankara, Turkey Yılmaz, Fatma Meriç; Department of Biochemistry, Faculty of Medicine, Yildirim Beyazit University, 06200 Ankara, Turkey Söylemezoğlu, Tülin; Institute of Forensic Sciences, Forensic Chemistry and Forensic Toxicology, Ankara University,06200 Ankara, Turkey Ünlü, Ali; Department of Biochemistry, Selcuk University Faculty of Medicine, 42200 Konya, Turkey |
| Fecha: | 2013-08-02 |
| Publicador: | International Journal of Mevlana Medical Sciences |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| Tema: | Toluene exposure; Aspartate Transaminase; Workers; Urinary Hippuric Acid; Industrial exposure |
| Descripción: | Toluene is one of the most widely used volatile organic compounds (VOCs) worldwide in many industrial fields such as industrial paints, adhesives, coatings, inks, and industrial cleaners and used as a starting material for the synthesis of a wide range of chemicals, including benzene. Hippuric acid is excreted in the urine and considered as colorless crystal structure which is often used in biomonitoring of exposure to industrial toluene. 295 non-exposed control subjects and 85 toluene-exposed workers were included to this study. Blood and urine samples were collected for biochemical, haematological and occupational parameters. According to occupational classification, painters were found to have highest urinary hippuric acid levels. Also, there was a weak positive correlation between serum aspartate transaminase (AST) and urinary hippuric acid levels (r=0.129, p=0.012). Serum AST levels may not be considered as a diagnostic tool for toluene-exposed workers. |
| Idioma: | Inglés |
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