Background: Annually, an estimated 8.2% of Canadians aged 18 or older are affected by major depressive disorder (MDD). Nearly half of those suffering from MDD will fail to achieve remission while also having an inadequate response to an initial and…

Macromolecular drug delivery systems, or nanocarriers, designed to improve the bioavailability of therapeutic and diagnostic agents, are promising tools for the site-specific delivery of drugs to the central nervous system (CNS). In particular, nanocarriers exhibit inherent activity that can be…

Uveal Melanoma (UM) is the most common intraocular tumor in adults. Liver metastasis is the leading cause of death in patients affected by this disease and in approximately 40% of the cases, metastasis occurs 10 years after initial diagnosis. Tumor…

Ultra Wideband (UWB) Impulse Radio (IR) technology has attracted considerable attention in the past few years due to its many desirable properties, such as the ability to penetrate through walls and ground, low power spectral density level, immunity to multipath…

Introduction: Current epidemiological evidence suggests that asthma and allergic conditions have an etiological component rooted in prenatal development. One of the associated risk factors is the exposure of the conceptus to prenatal maternal stress (PNMS). Current information on the effects…

Non-suicidal self-injury (NSSI) is defined as the deliberate destruction of one's own body tissue without suicidal intent and for purposes not socially sanctioned, thus excluding tattooing and piercing (Favazza, 1998). The high prevalence rate in both clinical and community studies…

The purpose of the present research program was to investigate IA children's language abilities during school age in order to see whether the difficulties reported in this population at younger ages persist (e.g., Gauthier & Genesee, 2011) or if they…

Flatworms of the genus Schistosoma are wide-spread and clinically significant parasites of humans in the tropics and sub-tropics. In evolutionary terms, they are representatives of the earliest metazoans to have evolved separate sexes, and to possess anatomically distinct central and…

Mine production scheduling may be long-term or short-term based on the time period considered and the final objective. The optimization goal of short-term production scheduling is to minimize the mining cost expected from a mine while satisfying operational constraints, such…

Self-definition and relatedness are fundamental personality developmental tasks that engage individuals across the entire lifespan (Blatt, 1974, Blatt & Luyten, 2009; Luyten & Blatt, 2013). Healthy psychological maturation requires the development of a sense of self that is differentiated, integrated,…