This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

L’objet de la présente étude est le développement, l’application et la diffusion de la technologie associée à divers types d’alliages de cuivre, en particulier l’alliage du plomb-bronze, en Grèce ancienne, dans ses colonies, ainsi qu’en Étrurie. Le plomb-bronze est un…

The methodology “b-learning” is a new teaching scenario and it requires the creation, adaptation and application of new learning tools searching the assimilation of new collaborative competences. In this context, it is well known the knowledge spirals, the situational leadership…

Currently, the Instituto Costarricense de Electricidad (ICE) offers
a range of customized solutions for enterprise customers-level
Information Technology (IT), and its main drawback response
time for delivery of these. Having strategic alliances collaborate
in resolving the situation.
This research is…

Defeasible Logic Programming (DeLP) is an extension of Logic Programming capturing common-sense reasoning features. The DeLP language can manage defeasible reasoning, allowing the representation of defeasible and non- defeasible knowledge. Since DeLP syntax is based on a PROLOG-like notation, the…

This work describes the ontology construction process for the development of an Intelligent System for the Organization and Retrieval of Knowledge in Biodiversity – SISBIO. The system aims at the production of strategic information for the biofuel chain Two main…

El objetivo de esta indagación documental y analítica es reflexionar sobre la ética del docente universitario en la gerencia del conocimiento,

dentro del marco de la investigación para la transformación del hombre y de la mujer. Se expone…

El diseño de tareas en los programas de formación de maestros se vincula al desarrollo del conocimiento necesario para realizar diferentes tareas profesionales- organizar el contenido matemático, interpretar el aprendizaje, gestionar la enseñanza. Se ejemplifica esta perspectiva en el caso…