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Aproximadamente 75 registro(s) hasta el momento: (journal)

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Recurso libre

Statistical methods for the analysis of high-throughput metabolomics data
Bartel, Jörg - Krumsiek, Jan - Theis, Fabian J.

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	Metabolomics is a relatively new high-throughput technology that aims at measuring all endogenous metabolites within a biological sample in an unbiased fashion. The resulting metabolic profiles may be regarded as functional signatures of the physiological state, and have been shown…
Fecha:	2013-03-22
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Engineering Microbes for Plant Polyketide Biosynthesis
Lussier, Francois-Xavier - Colatriano, David - Wiltshire, Zach - Page, Jonathan E. - Martin, Vincent J. J.

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	Polyketides are an important group of secondary metabolites, many of which have important industrial applications, including in the food and pharmaceutical industries. Polyketides are synthesized from one of three classes of enzymes differentiated by their biochemical features and product structure:…
Fecha:	2013-02-22
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Computer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein Engineering
Verma, Rajni; Jacobs University Bremen - Schwaneberg, Ulrich; RWTH Aachen University - Roccatano, Danilo; Jacobs University Bremen

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in this rapidly growing field. We…
Fecha:	2012-10-22
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Recent advances in rational approaches for enzyme engineering
Steiner, Kerstin; ACIB GmbH, c/o TU Graz, Petersgasse 14/4, 8010 Graz - Schwab, Helmut; ACIB GmbH, c/o TU Graz, Petersgasse 14/4, 8010 Graz and Institute of Molecular Biotechnology, TU Graz, Petersgasse 14/5, 8010 Graz, Austria

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	Enzymes are an attractive alternative in the asymmetric syntheses of chiral building blocks. To meet the requirements of industrial biotechnology and to introduce new functionalities, the enzymes need to be optimized by protein engineering. This article specifically reviews rational approaches…
Fecha:	2012-10-22
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Engineered fluorescent proteins illuminate the bacterial periplasm
Dammeyer, Thorben; NanoBioSciences Group Institut für Physikalische und Theoretische Chemie - Tinnefeld, Philip

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	The bacterial periplasm is of special interest whenever cell factories are designed and engineered. Recombinantely produced proteins are targeted to the periplasmic space of Gram negative bacteria to take advantage of the authentic N-termini, disulfide bridge formation and easy accessibility…
Fecha:	2012-11-22
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Analytical Techniques & Applications of Metabolomics in Systems Medicine and Systems Biotechnology
Villas-Boas, Silas G; The University of Auckland

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Editorial
Enlaces:	-
Fecha:	2013-02-18
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Meeting report: The seventh conference of the Hellenic Society for Computational Biology and Bioinformatics
Hamodrakas, Stavros J; University of Athens - Iliopoulos, Ioannis; University of Crete - Ouzounis, Christos A; Centre for Research & Technology Hellas AND Donelly Centre for Cellular & Biomolecular Research, University of Toronto - Bagos, Pantelis G; University of Central Greece - Promponas, Vasilis J; University of Cyprus

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	-
Fecha:	2013-06-16
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Structure-based Methods for Computational Protein Functional Site Prediction
KC, Dukka B; North Carolina A&T State University

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	Due to the advent of high throughput sequencing techniques and structural genomic projects, the number of gene and protein sequences has been ever increasing. Computational methods to annotate these genes and proteins are even more indispensable. Proteins are important macromolecules…
Fecha:	2013-11-11
Recurso:	Computacional and structural biotechnology journal

Recurso libre

Metabolomics in the identification of biomarkers of dietary intake
O’Gorman, Aoife - Gibbons, Helena - Brennan, Lorraine

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Peer-reviewed Article
Enlaces:	Traditional methods for assessing dietary exposure can be unreliable, with under reporting one of the main problems. In an attempt to overcome such problems there is increasing interest in identifying biomarkers of dietary intake to provide a more accurate measurement.…
Fecha:	2013-02-07
Recurso:	Computacional and structural biotechnology journal

Recurso libre

10.

The Role of INDY in Metabolic Regulation
Willmes, Diana M; Charité University School of Medicine Berlin - Birkenfeld, Andreas L; Charité University School of Medicine Berlin

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	Reduced expression of the Indy (I’m Not Dead Yet) gene in D. melanogaster and C. elegans extends longevity. Indy and its mammalian homolog mINDY (Slc13a5, NaCT) are transporters of TCA cycle intermediates, mainly handling the uptake of citrate via the…
Fecha:	2013-12-08
Recurso:	Computacional and structural biotechnology journal