This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

Se plantea la utilidad que representa para el alumno el aprendizaje significativo de la lengua escrita para acceder a la información como base para la construcción del conocimiento. Así, la atención pedagógica se centra en aspectos que debe poner en…

La thérapie génique, qui consiste à modifier le génome d'un individu, est la progression logique de l'application de la recherche fondamentale à la médecine. Au moment où l'on célèbre le décryptage du génome humain, surgissent les premières guérisons par la…

En este trabajo intento reflexionar acerca de lo que considero un problema olvidado entre los estudiosos de la filosofía de R. Descartes. ¿Es posible encontrar en el pensamiento cartesiano un ámbito fenomenológico que permita proporcionar un nuevo criterio de justificación…

The main purpose of this article is to contribute to a better understanding of the organizational sources pertaining to continuous innovation. This work identifies a set of best practices, which once integrated, create the innovative activities that help organizations to…

11-16 July 2010 Melbourne, Australia ICAP 2010 will be the first International Association of Applied Psychology (IAAP) Congress to be held in the Southern Hemisphere and the Australian Psychological Society (APS) is delighted to be hosting this prestigious, global event.…

The Requirements Engineering is fundamental part of the process of software development. Even if a program uses the most advanced technologies and has the best source code, it is not useful if it does not meet your requirements. The large…

It is a fact that mood-state knowledge is of particular relevance for the understanding of consumer behavior. The belief that it may be affected by the content of marketing communication and the context in which these communications appear was the…