This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

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This work presents the results of research on the relationship between the space displacement of the milk production and the change of seasonal variation of the acquisition and industrialization of the product in Brazil. The study showed that the knowledge…

2008

Este estudio se basa principalmente en los diferentes factores que han incidido en
las dificultades de aprendizaje de los estudiantes en la asignatura de Matemáticas, y como
el juego puede ser un apoyo para hacer seguimiento a los estudiantes y…

Below is a summary of the chapters contained in this thesis in order to facilitate the analysis and understanding.
The COSO I framework is the reference point of this thesis, which has as internal control components: control environment, risk assessment,…

A lo largo de los años, desde los orígenes de la humanidad, ha existido la constante necesidad de comunicarse, la cual se ha manifestado de distintas formas; verbal, no verbal, escrita, etc. hasta llegar a nuevas formas de comunicación más…

In addition to the efforts undertaken by research institutions to generate new knowledge and technologies, it is also necessary to promote the results of this research. Specifically, there is a need for an information system that aggregates, organizes and systematizes…