This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

The question of rationality and modernity has played a key role in defining the West’sunderstanding of itself in relation to “the other.” Much of this self-defining was done in a waythat privileged a western model of rationality, which itself was…

This article aims at identifying and characterizing the different configurations of the relevant factors related to administrative procedures, in order to learn about their behavior, and so about decision-making processes. Delays in administrative circuit concretion, users dissatisfaction and lack of…

Beginning with the premise that colonialism and the production of knowledge are intimately related, Christopher Schmidt-Nowara’s interests in this book lie in the versions of national and imperial histories elaborated by nineteenth-century Spanish and Antillean intellectuals. The production of knowledge…

The debate on the relationship between income, income inequality, and health of the last two decades has been based almost entirely on empirical considerations. The ideas prompting the debate are based on the concave relationship observed between health and income…

Concept maps are graphical representations of relationships among concepts that can be an effective tool for teaching, designing, and organizing information in a variety of library settings. Concept maps can be used wherever training or formal teaching occurs as a…

Total internal reflection microscopy (TIRM) measures the position of a Brownian particle above an interface by using its scattering of an evanescent wave. From the knowledge of the trajectory it is possible to reconstruct the interaction potential between the Brownian…

Esta investigación enfatiza la importancia del conocimiento matemático del profesorado para garantizar una educación matemática continua. Desde esta perspectiva de continuidad se explora el papel del docente de matemáticas en la transición de primaria a secundaria, un contexto especialmente adecuado…