This article explores commercial, academic, and national initiatives aimed at usingsequencing technologies to generate “actionable” genomic results that can beapplied to the clinical management of oncology patients. We argue that the term“actionable” is not merely a buzzword, but signals the…

Researchers and clinicians in the field of oncology have now entered the second decadeof targeted therapy, widely held to be a revolutionary new form of cancer therapyresearch. The present era is regarded as the end of brute empiricism: as laboratoryresearchers…

This article traces the history of research on resistance to drug therapy in oncology using scientometric techniques and qualitative analysis. Using co-citation analysis, we generate maps to visualize subdomains in resistance research in two time periods, 1975–1990 and 1995–2010. These…

The United States is struggling to provide health care in the face of ever increasing demand. As medical students continue their decades long march toward specialization, questions of how to provide generalist care become quickly intertwined with that of who…

Les médecins de famille, les pédiatres, les chiropraticiens et les physiothérapeutes sont parmi les professionnels de la santé les plus susceptibles de rencontrer des patients atteints d’une scoliose idiopathique adolescente. Les recherches démontrent que certaines lacunes existent à l’égard des…

L’abandon de la carrière chez les enseignants, généralement appelé l’attrition des enseignants dans les écrits scientifiques, a été l’objet de nombreuses études. La connaissance en est assez avancée dans certaines régions du monde, mais très peu de recherches ont étudié…

Los impresionantes cambios surgidos tras el inicio de la Revolución Industrial ayudaron a que de manera reiterada se buscaran soluciones a los diferentes problemas que se sucedían, uno tras de otro, como resultado del hacinamiento y las modificaciones sociopolíticas y…

Este trabajo busca conocer cómo se distribuyen los artefactos líticos en el componente inferior, del Pleistoceno final, del sitio Casa del Minero 1, Meseta Central de Santa Cruz.
Estos estudios se vinculan con los análisis previos realizados en el sitio…

The appearance and continuous growth of virtual communities on the web imposes the challenge of coping with the large amount of information and knowledge these communities produce. The Semantic Web with its set of standards and technologies provides the basic…

One goal of The Chemical Faculty and Environmental Engineering at the Technological Institute of Costa Rica is find environmentally friendly solutions for the development of the country and the region by incorporating scientific and technological knowledge in applied chemistry and…