| Título: | Computational tools for rational protein engineering of aldolases |
| Autores: |
Widmann, Michael; Institute of Technical Biochemistry, University of Stuttgart Pleiss, Jürgen; Institute of Technical Biochemistry, University of Stuttgart Samland, Anne K; Institute of Microbiology University of Stuttgart |
| Fecha: | 2012-11-13 |
| Publicador: | Computacional and structural biotechnology journal |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
| Tema: | No aplica |
| Descripción: | In this mini-review we describe the different strategies for rational protein engineering and summarize the computational tools available. Computational tools can either be used to design focused libraries, to predict sequence-function relationships or for structure-based molecular modelling. This also includes de novo design of enzymes. Examples for protein engineering of aldolases and transaldolases are given in the second part of the mini-review. |
| Idioma: | Inglés |
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