We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory
mechanisms. Ours is the first model to solve the complete nucleotide profile within filaments, a feature that determines the
dynamics and geometry of…

The action of adenine nucleotides on vascular endothelial cells is apparently mediated by the local flow conditions. Because
nucleotides are sequentially degraded from ATP - ADP - AMP -- adenosine by ecto-enzymes at the endothelial surface, it has been
hypothesized…

The analogous techniques of photoactivation of fluorescence (PAF) and fluorescence recovery after photobleaching
(FRAP) have been applied previously to the study of actin dynamics in living cells. Traditionally, separate
experiments estimate the mobility of actin monomer or the lifetime of…

The MIT Libraries has built a durable digital document repository called DSpace to house the
digital output of our faculty's research. DSpace will be a home for the digital documents our
faculty want to share with their colleagues around the…

Polymethine laser dyes which fluoresce in the near infrared in
organic solvents generally exhibit poor temporal stability at room
temperature. Two typical laser-pumped polymethine dyes in aqueous
solutions containing nonionic surfactants are investigated. Temporal
stability was improved 20-fold, as compared…

Presented in this paper is a robust control scheme for
controlling systems with time delays. The scheme is based on the Smith
controller and the LQG/LTR (Linear Quadratic Gaussian/Loop Transfer
Recovery) methodology. The methodology is applicable to undenvater
vehicle systems…

A matrix method for mooring system analysis is
extended to address the dynamic response of towed underwater
systems. Key tools are equivalent linearization and small perturbation
theory, and a pitching towfish model. Two examples of
application of the technique are…

The lasing efficiencies and photochemical stabilities of laser
dyes useful in the 710-1080-nm spectral region have been investigated
using a Q-switched ruby laser pumping source. The measured bleaching
rates P defined as the probability of irreversible decomposition of a dye

Thrust-producing harmonically oscillating foils are studied through force and power
measurements, as well as visualization data, to classify the principal characteristics of
the flow around and in the wake of the foil. Visualization data are obtained using
digital particle image…

Visualization studies of the flow behind an oscillating tapered cylinder are performed
at Reynolds numbers from 400 to 1500. The cylinder has taper ratio 40:1 and is
moving at constant forward speed U while being forced to oscillate harmonically
in…