This dissertation is a history of astronomy in three cultural locations in late Ottoman Egypt: the scholarly culture of Muslim ulama, the state institution of the Viceregal Observatory, and the Arabic press. Through an interwoven history of these cultures, the…

Aquatic Microbial Oxygenic Phototrophs (AMOP's) capture carbon dioxide from the atmosphere and fix it into organic molecules used for growth and proliferation. However, the mechanisms that decide how photosynthetically fixed carbon is allocated between the major sinks (proteins, lipids, and…

Malaria and diarrhea are major causes of illness and death in Africa. These preventable diseases take the biggest toll on children, mostly due to lack of education and adequate resources in the home. The purpose of the reported research project…

During the twentieth century, tobacco farmers in rural North Carolina quietly changed the relationship between the government and citizen in America . Flue-cured tobacco growers produced not only the finest cigarette leaf, but also new systems of marketing, regulating, and…

Protein domain prediction is a key step in characterizing protein structure, function, and evolution. However, the genome of Plasmodium falciparum, the causative agent of malignant malaria, remains poorly-annotated using standard approaches to domain prediction. We identified several general problems with…

Human cells are protected by cell-intrinsic mechanisms that specifically detect microbial pathogens and elicit innate immune response. Such activities are essential in restricting viral infections. Despite the extensive knowledge about cytoplasmic sensing processes, little is understood about the nuclear counterpart.…

This research explores the metabolic role of the gut microbiota in the global
obesity crisis and rising threat of global warming. Enteric microbiota in the rumen emit
methane as a by-product of metabolite degradation. Experiments – primarily on mice –

The antimicrobial effects of copper have been well established and may prove to be an effective means of reducing nosocomial or hospital-acquired infections. However, discussions surrounding the antimicrobial properties of copper-containing surfaces rarely address the effect of such materials on…

Conflicting reports have emerged as to whether entry of alpha-herpesvirus particles occurs by receptor-mediated membrane fusion or pH-dependent endocytosis, and whether the method of entry differs by cell type. At the other end of the virus replication cycle, it is…

The current state of science education in the United States is evolving to building a skills-based, rather than content-based, knowledge in its students, grades K-12. To this end, I have integrated my experience and understanding of molecular biology and educational…