This dissertation is a history of astronomy in three cultural locations in late Ottoman Egypt: the scholarly culture of Muslim ulama, the state institution of the Viceregal Observatory, and the Arabic press. Through an interwoven history of these cultures, the…

During the twentieth century, tobacco farmers in rural North Carolina quietly changed the relationship between the government and citizen in America . Flue-cured tobacco growers produced not only the finest cigarette leaf, but also new systems of marketing, regulating, and…

Protein domain prediction is a key step in characterizing protein structure, function, and evolution. However, the genome of Plasmodium falciparum, the causative agent of malignant malaria, remains poorly-annotated using standard approaches to domain prediction. We identified several general problems with…

Human cells are protected by cell-intrinsic mechanisms that specifically detect microbial pathogens and elicit innate immune response. Such activities are essential in restricting viral infections. Despite the extensive knowledge about cytoplasmic sensing processes, little is understood about the nuclear counterpart.…

Malaria and diarrhea are major causes of illness and death in Africa. These preventable diseases take the biggest toll on children, mostly due to lack of education and adequate resources in the home. The purpose of the reported research project…

Although we represent other people in terms of both what they look like and how they behave, these two aspects of person knowledge have rarely been studied together. While vision scientists have focused on the processing of faces and bodies,…

With the advancement of technology, we are able to collect, store, and transmit an ever-increasing volume of data. However, our ability to extract useful patterns from this massive amount of data is still lagging behind. Machine learning and signal processing…

My dissertation centers on the meaning of dreams as interpreted by literati in the late Ming (1368-1644), viewed through the lens of the 1636 encyclopedia Forest of Dreams. This thirty-four-juan tome is the largest extant Chinese dream encyclopedia and includes…

This research explores the metabolic role of the gut microbiota in the global
obesity crisis and rising threat of global warming. Enteric microbiota in the rumen emit
methane as a by-product of metabolite degradation. Experiments – primarily on mice –

The antimicrobial effects of copper have been well established and may prove to be an effective means of reducing nosocomial or hospital-acquired infections. However, discussions surrounding the antimicrobial properties of copper-containing surfaces rarely address the effect of such materials on…