One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

(cont.) which is expected, given their additional knowledge resources. The respondents' urgency in looking for the relevant knowledge is the primary explanation for this difference between the two networks. This difference in knowledge networking among the different groups did not…

This thesis examines the evolution of Internet based knowledge networks (e-knowledge networks) in the domain of sustainable development. The objective of this thesis is to use an engineering systems approach to understand knowledge networks, identify the barriers to their sustainability…

An automatic disassembly cell requires of a
computer vision system for recognition and localization of
the products and each of theirs components. The detection
of occlusions adds more information to the knowledge base
to identify components and products, and generate…

BACKGROUND:A variety of definitions of evidence-based practice (EBP) exist. However, definitions are in themselves insufficient to explain the underlying processes of EBP and to differentiate between an evidence-based process and evidence-based outcome. There is a need for a clear statement…

BACKGROUND:Primary prevention of breast cancer through prophylactic mastectomy can reduce the risk of malignancy in high-risk individuals. No type of mastectomy completely removes all breast tissue, but a subcutaneous mastectomy leaves more tissue in situ than does a simple mastectomy.CASE…

RESUMO: O conhecimento do comportamento hidrossedimentológico de uma bacia hidrográfica é fundamental para a adequada gestão e uso de seus recursos hídricos. Este traballho objetivou realizar, a partir dos dados hidrossedimentométricos da Bacia do Rio Piquiri, um diagnóstico sobre o…

Evolutionary algorithms (EAs) are merely blind search algorithms, which only make use of the relative fitness of solutions, but completely ignore the nature of the problem. Their performance can be improved by using new multirecombinative approaches, which provide a good…

The Internet is the world's largest knowledge common and the information source of first resort. Much of this information is open and freely available. However, there are organizations and companies today that are trying to close off the Internet commons…