Understanding the biological signals encoded in a genome is a key challenge of computational biology. These signals are encoded in the four-nucleotide alphabet of DNA and are responsible for all molecular processes in the cell. In particular, the genome contains…

The shift towards global networking brings with it many opportunities and challenges. In this paper, we discuss key technologies in achieving global semantic interoperability among heterogeneous information systems, including both traditional and web data sources. In particular, we focus on…

This thesis examines the evolution of Internet based knowledge networks (e-knowledge networks) in the domain of sustainable development. The objective of this thesis is to use an engineering systems approach to understand knowledge networks, identify the barriers to their sustainability…

by Peter L. Grant., Thesis (S.M.M.O.T.)--Massachusetts Institute of Technology, Sloan School of Management, Management of Technology Program, 2000., Includes bibliographical references (p. 105-108).

by Michael Luke Murtaugh., Thesis (M.S.)--Massachusetts Institute of Technology, Program in Media Arts & Sciences, 1996., Includes bibliographical references (p. 75-76).

by Christopher Granger Atkeson., Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences, Technology, and Management, Dept. of Brain and Cognitive Sciences, 1986., MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE, Bibliography: leaves 143-154.

This thesis will explore the design and optimization of a peer-to-peer network application as a solution to complex content management problems. Currently, most content management systems are expensive, cumbersome and inflexible custom solutions that require knowledge workers to change their…

Signature schemes are fundamental cryptographic primitives, useful as a stand-alone application, and as a building block in the design of secure protocols and other cryptographic objects. In this thesis, we study both the uses that signature schemes find in protocols,…

Knowledge of how groups of people interact is important in many disciplines, e.g. organizational behavior, social network analysis, knowledge management and ubiquitous computing. Existing studies of social network interactions have either been restricted to online communities, where unambiguous measurements about…

The Triple β-Spiral is a novel protein structure that plays a role in viral attachment and pathogenesis. At present, there are two Triple β-Spiral structures with solved crystallographic coordinates - one from Adenovirus and the other from Reovirus. There is…