Triazolylmethyl oxazolidinones are novel potent antibacterial agents recently synthesized in our laboratory. PURPOSE. Development of a rapid and specific LC-MS method for evaluating the stability of three potentially active antibacterial triazolylmethyl oxazolidinone compounds, namely PH-27, PH-38 and PH-41, in human…

Globally, privacy is under threat. To many in academia, there is little hope in preserving active domains of seclusion, secrecy or anonymity within an increasingly risk averse, surveillance-networked, global society. Further, scholars within the field of surveillance studies have suggested…

The “Lippmann-Dewey Debate” became widely discussed in the 1980s and 1990s in U.S. media and communication studies, in large part through the influence of James Carey. While Carey’s initial writing on the Lippmann-Dewey exchange was insightful, by 1987, his characterization…

Globally, privacy is under threat. To many in academia, there is little hope in preserving active domains of seclusion, secrecy or anonymity within an increasingly risk averse, surveillance-networked, global society. Further, scholars within the field of surveillance studies have suggested…

The “Lippmann-Dewey Debate” became widely discussed in the 1980s and 1990s in U.S. media and communication studies, in large part through the influence of James Carey. While Carey’s initial writing on the Lippmann-Dewey exchange was insightful, by 1987, his characterization…

When presidents attempt to transform a country, they do so by utilizing a keen understanding of the status quo and a knowledge of how to challenge it—and most often, they challenge it by performing a key speech. Within this speech,…

The frequency of the electronic media as a source of harm to an  individual’ s  reputation is growing  as it is a source of  knowledge on the information highway and has the potential to leave indelible marks on careers. 

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The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in this rapidly growing field. We…

Enzymes are an attractive alternative in the asymmetric syntheses of chiral building blocks. To meet the requirements of industrial biotechnology and to introduce new functionalities, the enzymes need to be optimized by protein engineering. This article specifically reviews rational approaches…