| Título: | Mutations at pipX suppress lethality of PII-deficient mutants of Synechococcus elongatus PCC 7942 |
| Autores: |
Espinosa Manzano, Javier Castells Rico, Miguel Ángel Laichoubi, Karim Boumediene Contreras de Vera, Asunción |
| Fecha: |
2010-10-28 2010-10-28 2009 2009-08 |
| Publicador: | RUA Docencia |
| Fuente: |
 |
| Tipo: | info:eu-repo/semantics/article |
| Tema: |
Cyanobacteria Genética |
| Descripción: |
The PII proteins are found in all three domains of life as key integrators of signals reflecting the balance of nitrogen and carbon. Genetic inactivation of PII proteins is typically associated with severe growth defects or death. However, the molecular basis of these defects depends on the specific functions of the proteins with which PII proteins interact to regulate nitrogen metabolism in different organisms. In Synechococcus elongatus PCC 7942, where PII forms complexes with the NtcA coactivator PipX, attempts to engineer PII-deficient strains failed in a wild-type background but were successful in pipX null mutants. Consistent with the idea that PII is essential to counteract the activity of PipX, four different spontaneous mutations in the pipX gene were found in cultures in which glnB had been genetically inactivated. This work was supported by grants BFU2006-12424 and ACOMP06/083. M.A.C. is the recipient of a predoctoral fellowship from the Universidad de Alicante. |
| Idioma: | Inglés |
1 Choosing the correct paradigm for unknown words in rule-based machine translation systems por Sánchez Cartagena, Víctor Manuel,Esplà Gomis, Miquel,Sánchez Martínez, Felipe,Pérez Ortiz, Juan Antonio | 6 Análisis Real de Varias Variables II. Problemas (27-3-2013) por Conde Calero, Juan Manuel |
2 Using external sources of bilingual information for on-the-fly word alignment por Esplà Gomis, Miquel,Sánchez Martínez, Felipe,Forcada Zubizarreta, Mikel L. | 7 Introducción a mirada/s trans/identitarias,Introduction to trans-identitary look(s) por Amaro Quintas, Ángel Manuel |
3 | 8 |
4 | 9 |
5 Los espacios periurbanos en el área ibérica contestana: las novedades y algunas reflexiones históricas por Sala Sellés, Feliciana | 10 Matrimonio igualitario y parentesco: discursos, hegemonías y acontecimiento,Egalitarian marriage and kinship: discourses, hegemony and event por Buzaglo, Analía,Morandi, Mariela,Culla, Mónica |