| Título: | An in vivo study of the effect of an extended single exposure of Helium-Neon (632.8 nm) laser on collagen concentration in healing incisional wounds / |
| Autores: | Ross, Ian William |
| Fecha: | 1990 |
| Publicador: | McGill University |
| Fuente: |
Ver documento |
| Tipo: | Electronic Thesis or Dissertation |
| Tema: |
Health Sciences, Medicine and Surgery. Health Sciences, Radiology. |
| Descripción: |
The effect of a single exposure of He-Ne laser on collagen content was studied in vivo using laboratory animals. A standardized 1.5 cm full thickness skin incision was made on the dorsum of 24 Sprague-Dawley rats. The rats were divided into six equal size groups, three groups functioning as controls and three groups functioning as experimental. The experimental animals were irradiated with He-Ne laser four days post-incision for 16 minutes to deliver a total dose of 5.99 J/cm$ sp2$. On days 6, 10 and 14 post-incision, control and experimental animals had the healing wounds excised for analysis of collagen content by assaying spectrophotometrically the hydroxyproline content within the tissue samples. The results of the hydroxyproline content were analyzed using independent-groups t-test and analysis of variance. It was demonstrated that even though the mean values of hydroxyproline within the experimental groups were higher than the respective control groups, no statistical significance could be attributed to this observation. |
| Idioma: | en |
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