| Título: | Experimental studies of acinar-islet tissue ration in puppies. |
| Autores: | Chun, John. Y. |
| Fecha: | 1964 |
| Publicador: | McGill University - MCGILL |
| Fuente: |
 |
| Tipo: | Electronic Thesis or Dissertation |
| Tema: | Experimental Surgery. |
| Descripción: | Almost one hundred years ago Paul Langerhans (1) described the pancreatic islet cells. Another 50 years had passed before its physiological significance had become clear, following the studies of Laguesse (2). On the basis of histological observations, particularly referring to profuse vascularization of the islets, Laguesse suggested in 1893, that islet cell have an endocrine function. The classical experiments of Banting and Best (3) in 1922 lead to the identification of the hormone insulin and consequently to the treatment of diabetes. According to present knowledge, insulin is secreted by Beta cells. It has been shown that the insulin content of the splenic portion of the dog's pancreas is much higher than the duodenal portion. |
| Idioma: | en |
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