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Título: Disturbance in the control of heart rate during exercise following intracardiac repair : contribution of the cardiopulmonary bypass surgery
Autores: Grief, Gail
Fecha: 1992
Publicador: McGill University
Fuente: Ver documento
Tipo: Electronic Thesis or Dissertation
Tema: Biology, Animal Physiology.
Health Sciences, Medicine and Surgery.
Descripción: This study was designed therefore, to investigate potential contributions of the cardiopulmonary bypass (CPB) procedure to the chronotropic limitation during exercise in surgically corrected CHD adolescents. Patients were divided into 3 groups: operated ventricular septal defect, where CPB is required (VSDop: n = 15); VSD closed spontaneously, no surgery or CPB required (VSDnop: n = 17); and operated patent ductus arteriosus, where surgery does not require CPB (PDA: n = 20). Fifteen healthy age-matched subjects served as the control group (C). All subjects were submitted to a graded maximal exercise cycle egometer test and completed 3 levels of submaximal exercise. Maximal oxygen consumption was similar in all groups. Cardiac index and stroke volume index at rest and during submaximal exercise were slightly lower in VSDop and PDA than VSDnop and C, however no statistical significance was found. The heart rate at rest was similar in all groups, however it was significantly lower in VSDop than all other groups. (Abstract shortened by UMI.)
Idioma: en