Single-particle reconstruction of vitrified samples (cryogenic electron microscopy, or









cryo-EM) provides structural information for a large variety of biological molecules,









ranging from…

Machine learning is the science of discovering knowledge from data and making decisions based on this learnt structure. It has grown into a broad discipline that has established many statistical and computational learning principles. We are surrounded by the applications…

This dissertation sets a detailed, technical history of ideas of Dutch-born lens maker and natural philosopher Nicolas Hartsoeker (1656-1725). Hartsoeker's case exemplifies the kinds of intellectual journeys a university-educated man with technical skills undertook to navigate the chaos and uncertainty…

The Nusayri-'Alawis, the syncretistic Shiite sect currently prominent in Syria, are some of the only survivors of the heterodox cults of Early Islam. For theological and precautionary reasons they are forbidden from sharing their beliefs with outsiders. As a result,…

The central goal of compressed sensing is to capture attributes of a signal using very few measurements. The initial publications by Donoho and by Candes and Tao have been followed by applications to image compression, data streaming, medical signal processing,…

This dissertation maps the ethnographic and archaeological work of the Dutch architects Aldo van Eyck and Herman Haan between 1947 and 1967, including van Eyck's writings, editorial work, and encounter with the sub-Saharan Dogon people, and Haan's expeditions and ethnographic…

Visual recognition remains one of the grand goals of artificial intelligence research. One major challenge is endowing machines with human ability to recognize tens of thousands of categories. Moving beyond previous work that is mostly focused on hundreds of categories,…

This dissertation is about family history and the constitution of the social among the Abenaki, an aboriginal people often associated with the Odanak reserve in southern Quebec. It is an ethnography of belonging among a people whose status as aboriginal…

This dissertation examines the historical evolution of Korean print culture by studying the ways in which the reading public expanded its boundary beyond the confines of canonical texts in the nineteenth and early twentieth centuries. In this dissertation, I analyze…

This dissertation chronicles the emergence of economic calculation as an analytical, argumentative, and moral tool in British politics in the half-century after the 1688 Revolution. During Britain's "financial revolution," novel questions about the nation's "Trade & Revenue" were contested in…