Software technology is creating a ubiquitous context for human living and learning in which new modes of interaction are gradually being incorporated. At the same time, interaction with Internet-based learning systems has evolved from using the traditional access from a…

From the earliest hardware and software days to the internet era, complexity of computer systems has been something computer scientists, engineers, and programmers have had to deal with. Important fields of research and technology have originated, developed, or matured as…

Following a classical conception of Artificial Intelligence (one that aims a definition of cognitive mechanisms and their implementation in computers), this thesis explores the problem of knowledge organization. In particular, it draws attention to the linguistic and semantic memory, trying…

Biclustering has become a very popular data mining technique due to its ability to explore at the same time two different dimensions, as opposed to clustering techniques, that make use of only one dimension. Gene expression data offer a suitable…

La separación de biomoléculas de alto valor añadido, con tamaño y características similares como la albúmina de suero bovino (BSA) y la lactoferrina (LF), representa uno de los retos más difíciles en la industria bioquímica. Durante 100 años las técnicas…

Breast Cancer Resistance Protein (BCRP, ABCG2) and P-glycoprotein (P-gp, ABCB1, MDR1) are
members of the G and B subfamily of the ATP-binding cassette (ABC) efflux transporters, respectively.
Both transporters use the energy of ATP hydrolysis for substrate efflux.…

Molts problemes de la vida quotidiana estan plens de decisions multi-classe. En l'àmbit del Reconeixement de Patrons, s'han proposat moltes tècniques d'aprenentatge que treballen sobre problemes de dos classes. No obstant, la extensió de classificadors binaris al cas multi-classe és…

With the increasing demand for composite materials by the industry, the adhesive joints emer ge as an attractive alternative to traditional mechanical joints. The latter require as a preliminary step, the drilling of the laminates with consequent damage to the…

En esta tesis doctoral se propone la utilización de una metodología espacial para la integración de construcciones rurales en su entorno, mediante la utilización de un sistema de evaluación de criterios múltiples (ECM), en un entorno web asistido por la…

This dissertation sets out to examine the conceptual domains of CHANGE and
POSSESSION by selecting two main verbal classes, namely entity-specific change-ofstate verbs for the domain of CHANGE and contribute verbs for that of POSSESSION.
The most important step consisted…