This study is intended to furnish an explicability of hunter-gather's organizational model on the lithic technology. The fieldwork area is the Imjin-Hantan River Area (the IHRA) located at the midwestern part of the Korean Peninsula. The archaeological sites included in…

Background and rationale. Cerebral palsy (CP) is one of the most common disabling disorders of childhood and constitutes a substantial portion of pediatric rehabilitation. This condition demands comprehensive rehabilitation using age-appropriate tasks and activities and encompassing aspects of body function…

Uveal melanoma is the most common primary intraocular malignant tumour in adults. Despite improvements in the diagnosis and treatment of the primary tumour, patients continue to have the same mortality rate as several decades ago, reflecting our poor understanding of…

Vitamin D is a precursor to a steroid hormone, 1,25 dihydroxyvitamin D (1,25(OH)2D). After its discovery and the characterization of its receptor, the vitamin D receptor (VDR), it was initially thought only to be involved in calcium homeostasis, but further…

This thesis addresses the general problem of maintaining robust automatic speech recognition (ASR) performance under diverse speaker populations, channel conditions, and acoustic environments. To this end, the thesis analyzes the interactions between environment compensation techniques, frequency warping based speaker normalization,…

Extreme rainfall events may have catastrophic impacts on the population and infrastructures, therefore it is essential to have accurate knowledge of extreme rainfall characteristics. Moreover, both the scientific community and policymakers have recently shown a growing interest in the potential…

In this thesis, we present a strongly coupled data fusion architecture within a Bayesian framework for modeling the bi-directional influences between the scene and object classification mechanisms. A number of psychophysical studies provide experimental evidence that the object and the…

Rapid progress has been made toward understanding the significance of CDK inhibitor proteins (CKIs) in the regulation of cell cycle progression. The overall goal of this study has been targeted to further expand our knowledge of CKI function through the…

The role of prion protein (PrPC) as a crucial factor in the pathogenesis of the Transmissible Spongiform Encephalopathies (TSE's) is well known. However, the physiologic role of this highly conserved protein in vivo is thus far, largely unknown. In vitro…

Aminoglycosides are broad spectrum antibiotics that act by binding to 16S rRNA of bacteria. The wide spread of aminoglycoside resistance threatens the use of these important medicines. Two general approaches can be used to address the aminoglycoside resistance problem. One…