La separación de biomoléculas de alto valor añadido, con tamaño y características similares como la albúmina de suero bovino (BSA) y la lactoferrina (LF), representa uno de los retos más difíciles en la industria bioquímica. Durante 100 años las técnicas…

Breast Cancer Resistance Protein (BCRP, ABCG2) and P-glycoprotein (P-gp, ABCB1, MDR1) are
members of the G and B subfamily of the ATP-binding cassette (ABC) efflux transporters, respectively.
Both transporters use the energy of ATP hydrolysis for substrate efflux.…

En esta tesis doctoral se propone la utilización de una metodología espacial para la integración de construcciones rurales en su entorno, mediante la utilización de un sistema de evaluación de criterios múltiples (ECM), en un entorno web asistido por la…

Generally, drilling fluids may be multicomponent suspensions, emulsions and/or foams, basically consisting of a base fluid (oil or water), viscosifiers/thinners (clays, biopolymers, etc) and weighting agents (salts) designed to lubricate during drilling operation and removal the cuttings, among others functions.…

Saltwater Chronicles investigates the notion of “islandness” in contemporary Newfoundland readership through two in-depth case studies of book clubs as representational spaces in the elaboration of local knowledge and identities. We demonstrate how select Newfoundland readers perform acts of regeneration…

Eighty years after the discovery of penicillin, the interest of this ß-lactam antibiotic at industrial level is still remarkable. Despite the good background knowledge, little is known on how Penicillin chrysogenum became a good penicillin overproducer, and much of the…

Background: Recently, proteins and peptides have become an added value to foodstuffs due to new knowledge
about its structural analyses as related to antioxidant and anticancer activity. Our goal was to evaluate if protein
fractions from cacao seeds show antitumor…

Resource management and performance models constitute important aspects for parallel applications' performance analysis and tuning. Defining performance models associated with the application structure has been proven useful for implementing dynamic tuning tools. However, for extending this strategy to complex pplications…

Understanding how materials deform and break is a subject of critical importance in industry. At the same time, it requires from the knowledge of the basic processes governing the phenomenon and hence, fundamental physics research is a must. The presence…

From the earliest hardware and software days to the internet era, complexity of computer systems has been something computer scientists, engineers, and programmers have had to deal with. Important fields of research and technology have originated, developed, or matured as…