The Triple β-Spiral is a novel protein structure that plays a role in viral attachment and pathogenesis. At present, there are two Triple β-Spiral structures with solved crystallographic coordinates - one from Adenovirus and the other from Reovirus. There is…

The contribution of this thesis is to provide a tractable framework for supply chains and revenue management problems subject to uncertainty that gives insight into the structure of the optimal policy and requires little knowledge of the underlying probability distributions.…

We strain our eyes, cramp our necks, and destroy our hands trying to interact with computer on their terms. At the extreme, we strap on devices and weigh ourselves down with cables trying to re-create a sense of place inside…

A transmitter antenna array has the ability to direct data simultaneously to multiple receivers within a wireless network, creating potential for a more integrated view of algorithmic system components. In this thesis, such a perspective informs the design of two…

All intelligence relies on search - for example, the search for an intelligent agent's next action. Search is only likely to succeed in resource-bounded agents if they have already been biased towards finding the right answer. In artificial agents, the…

Recent advances in biology have afforded scientists with the knowledge that polysaccharides play an active role in modulating cellular activities. Glycosaminoglycans (GAGs) are one such family of polysaccharides that play a very important role in regulating the functions of numerous…

Nearly 2% of all live births are very premature (gestational age less than 32 weeks), and 50% of all new cases of cerebral palsy occur in survivors of premature birth (gestational age less than 37 weeks). Because of their underdeveloped…

(cont.) algorithm to identify the regulatory models from protein-DNA binding and gene expression data. These models to a large extent agree with the knowledge of gene regulation pertaining to the corresponding regulators. The three works in this thesis provide a…

This thesis explores a novel approach to visual speech modeling. Visual speech, or a sequence of images of the speaker's face, is traditionally viewed as a single stream of contiguous units, each corresponding to a phonetic segment. These units are…

Satellite and wireless networks operate over time varying channels that depend on attenuation conditions, power allocation decisions, and inter-channel interference. In order to reliably integrate these systems into a high speed data network and meet the increasing demand for high…