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Aproximadamente 30 registro(s) hasta el momento: (journal)

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Metabolism of isorhynchophylline in rats detected by LC-MS
Wang, Wei; Division of Metabolic Engineering, Institute of Natural Medicine, University of Toyama - Ma, Chao-Mei; Division of Metabolic Engineering, Institute of Natural Medicine, University of Toyama - Hattori, Masao; Division of Metabolic Engineering, Institute of Natural Medicine, University of Toyama

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	PURPOSE This paper investigates the metabolic fate of isorhynchophylline (ISOR) as a main bioactive oxindole alkaloid in the traditional Chinese medicine. METHODS After oral administration of ISOR to rats, plasma, bile, urine and feces were analyzed by LC-MS. Hydroxylation of…
Fecha:	2010-02-02
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Validation of Bone Marrow Derived Dendritic Cells as an Appropriate Model to Study Tumor-Mediated Suppression of DC Maturation through STAT3 Hyperactivation
Alshamsan, Aws; University of Alberta - Hamdy, Samar; University of Alberta - Saswati Das, Saswati Das; University of Alberta - Lavasanifar, Afsaneh - Samuel, John; University of Alberta - El-Kadi, Ayman O.S.; University of Alberta

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	PURPOSE: Tumors can escape immune eradication by harnessing dendritic cell (DC) maturation. However, DC types used as in vitro models to study tumor-mediated immunosuppression possess fundamental variability that could influence research outcomes. Therefore, we assessed the behavior of two distinct…
Fecha:	2010-02-02
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	PURPOSE This paper investigates the metabolic fate of isorhynchophylline (ISOR) as a main bioactive oxindole alkaloid in the traditional Chinese medicine. METHODS After oral administration of ISOR to rats, plasma, bile, urine and feces were analyzed by LC-MS. Hydroxylation of…
Fecha:	2010-02-02
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

The Two Faces of Pharmacokinetics
Rescigno, Aldo

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	There are two main branches of Mathematics: Calculus and Geometry; in Physics there are Constructive Theories and Principle Theories. Similarly in Pharmacokinetics we can build models with two opposite approaches, the bottom-up and the top-down point of view. In this…
Fecha:	2010-02-22
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

The Two Faces of Pharmacokinetics
Rescigno, Aldo

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	There are two main branches of Mathematics: Calculus and Geometry; in Physics there are Constructive Theories and Principle Theories. Similarly in Pharmacokinetics we can build models with two opposite approaches, the bottom-up and the top-down point of view. In this…
Fecha:	2010-02-22
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Bicarbonate supplementation as a preventive way in statins-induced muscle damage
Kobayashi, Masaki - Kagawa, Toshiki - Narumi, Katsuya - Itagaki, Shirou - Hirano, Takeshi - Iseki, Ken; Hokkaido University

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	ABSTRACT – Purpose. The aim of this study was to evaluate the bicarbonate-induced improvement of statins, cerivastatin, simvastatin acid and lovastatin acid -induced apoptosis using rat myoblast cell line (L6) as a model of in vitro skeletal muscle and of…
Fecha:	2008-02-20
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Drug Delivery Properties of Macroporous Polystyrene Solid Foams
Canal, Cristina; Technical University of Catalonia - Aparicio, Rosa Maria - Vilchez, Alejandro - Esquena, Jordi - García-Celma, Maria José

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	Purpose. Polymeric porous foams have been evaluated as possible new pharmaceutical dosage forms. Methods. These materials were obtained by polymerization in the continuous phase of highly concentrated emulsions prepared by the phase inversion temperature method. Their porosity, specific surface and…
Fecha:	2012-02-18
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Nanotherapeutics to Overcome Conventional Cancer Chemotherapy Limitations
Chidambaram, Moorthi - Manavalan, R. - Kathiresan, K.

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	Cancer is one of the major causes of death worldwide and chemotherapy is a major therapeutic approach for the treatment which may be used alone or combined with other forms of therapy. However, conventional chemotherapy suffers lack of aqueous solubility,…
Fecha:	2011-02-16
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	Purpose. Polymeric porous foams have been evaluated as possible new pharmaceutical dosage forms. Methods. These materials were obtained by polymerization in the continuous phase of highly concentrated emulsions prepared by the phase inversion temperature method. Their porosity, specific surface and…
Fecha:	2012-02-18
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences

Recurso libre

10.

Bioadhesive properties of β-limit dextrin
QI, XIN; Glycologic Limited - Tester, Richard F; Glycologic Limited

Formato:	info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion,
Enlaces:	Purpose. β-Limit dextrin has been studied for many years as a means to investigate the internal structures of amylose and amylopectin. However its role as an excipient in the pharmaceutical industry has never been reported. This paper is the first…
Fecha:	2011-02-16
Recurso:	Journal of Pharmacy and Pharmaceutical Sciences