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Purpose: To determine the inclusion of women and the sex-stratification of results in moxifloxacin Clinical Trials (CTs), and to establish whether these CTs considered issues that specifically affect women, such as pregnancy and use of hormonal therapies. Previous publications about…

The analytical approximate technique developed by Wu et al. for conservative oscillators with odd nonlinearity is used to construct approximate frequency-amplitude relations and periodic solutions to the relativistic oscillator. By combining Newton's method with the method of harmonic balance, analytical…

The synthesis of a GSK 2nd generation inhibitor of the hepatitis C virus, by enantioselective 1,3-dipolar cycloaddition between a leucine derived iminoester and tert-butyl acrylate, was studied. The comparison between silver(I) and gold(I) catalysts in this reaction was established by…

Regulatory pressures and strong competitiveness, as well as the need to control costs and remain up to date with information technologies have turned outsourcing into a basic tool at the disposal of financial entities. Our paper has as its aim…

A paradigm for modelling and analysing Home Automation Systems is introduced, based on Multi-Agent System theory. A rich and versatile environment for Home Automation System simulation is constructed for investigating the performances of the system. The exploitation of limited resources…

This article presents a model of robotic control system inspired by the human neuroregulatory system. This model allows the application of functional and organizational principles of biological systems to robotic systems. It also proposes appropriate technologies to implement this proposal,…

Reply to comment by L. Fenoglio-Marc et al. on “On the steric and mass-induced contributions to the annual sea level variations in the Mediterranean Sea”., This work is supported by the Spanish Science and Technology Ministry Project ESP2006-11357.

Enantiomerically enriched cyanohydrin O-phosphates, prepared
by enantioselective cyanophosphorylation of α,β-unsaturated
aldehydes, react regioselectively at the γ-position
with organocuprates derived from alkyl Grignard reagents
and CuCN to afford chiral γ-alkyl-substituted α,β-unsaturated
nitriles. The configuration of the new C–C double bond
is…

By applying Gaussian optics we propose a new matrix formula model for intraocular lens (IOL) calculation that yields not only IOL optical power for a particular eye but also an evaluation of the bending factor of different IOL optical designs.…