Purpose: We studied the efficacy and safety of bortezomib (BOR) for treatment of multiple myeloma in comparison with thalidomide (THAL) by reference to adverse events, and searched for laboratory markers that could be used for prognostication of patients.
Methods:…

Purpose: We studied the efficacy and safety of bortezomib (BOR) for treatment of multiple myeloma in comparison with thalidomide (THAL) by reference to adverse events, and searched for laboratory markers that could be used for prognostication of patients.
Methods:…

15-Deoxy-Δ12,14-prostaglandin J2 (15dPGJ2) has been recently proposed as a potent anti-inflammatory agent. However, the mechanisms by which 15dPGJ2 mediates its therapeutic effects in vivo are unclear. We demonstrate that 15dPGJ2 at micromolar (2.5–10 µM) concentrations induces the expression of heme…

Previously we described a large collection of cloned human DNAs that encode chemically defined missense mutations
within the ribosomal protein S14 sequence. We determined that biologically inactive (i.e. null) alleles resulted primarily
from point mutations targeted to two internal segments…

Electrodeposition of Pt nanoparticles under
potentiostatic conditions was performed on several types of carbon electrode supports: commercial macroporous carbon (a three-dimensional electrode), glassy carbon and
graphite. Conducting polymers (poly-aniline and poly-oaminophenol) were also used. The platinum nanoparticles were obtained by…

When aberrations are small, it is possible to use wave aberration variance to obtain the position of the best image plane in both conventional and holographic optical systems. However, when aberrations increase, this measurement is not sufficient and it does…

In this paper we present the theoretical analysis and experimental results of a holographic collimator made in silver halide sensitized gelatin. Diffraction efficiency up to 70% over the whole plate and wave aberration as low as 20-lambda in the maximum…

I describe the development of a group in North London that aimed to increase the involvement of carers in the development and monitoring of mental health services across the borough. I enabled the carers to evaluate their experiences of the…

Se identifican en fracciones de membranas plasmáticas aisladas de células ascíticas AS-30D de hepatocarcinoma de rata, tres glicoproteínas de 125 kDa, 115 kDa y 105 kDa (gp125, gp115 y gp105) que son adenililadas utilizando ATP como sustrato. Esta adenililación es…

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