The use of ribonucleoside phosphoramidites protected at the 2$ sp prime$-hydroxyl with alkylsilyl ethers was developed for the solid phase synthesis of oligoribonucleotides. A series of pentadecameric oligomers of various base composition was synthesized using this methodology and a complete…
Fecha:
1986
Recurso:
McGill University - MCGILL
CIC - Centro de Información y Conocimiento Johannes Gutenberg ®