One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

Purpose – The idea that knowledge management can be a potential source of competitive advantage has gained strength in the last few years. However, a number of business actions are needed to generate an appropriate environment and infrastructure for knowledge…

(cont.) which is expected, given their additional knowledge resources. The respondents' urgency in looking for the relevant knowledge is the primary explanation for this difference between the two networks. This difference in knowledge networking among the different groups did not…

This paper presents a version of frames suitable for representing knowledge for a class of reconition problems. An initial section gives an intuitive model of frames, and illustrates a number of desirable features of such a representation. A more technical…

This thesis examines the evolution of Internet based knowledge networks (e-knowledge networks) in the domain of sustainable development. The objective of this thesis is to use an engineering systems approach to understand knowledge networks, identify the barriers to their sustainability…

Desde el punto de vista de la conservación, conocer la abundancia, la diversidad, y los patrones de actividad de un ensamble herpetológico son medulares para comprender la dinámica de la comunidad y el modo de cómo es utilizado el hábitat.…

Over the next five years, computer games will find their way into a vast number of American homes, creating a unique educational opportunity: the development of "computer coaches" for the serious intellectual skills required by some of these games. From…

Evolutionary algorithms (EAs) are merely blind search algorithms, which only make use of the relative fitness of solutions, but completely ignore the nature of the problem. Their performance can be improved by using new multirecombinative approaches, which provide a good…

Using an audiovisual perception task, two groups of native English listeners
(monolinguals, and L2 learners of Spanish) were asked to identify
which /p,t,k/ tokens had been produced by native English speakers
and which ones by foreigners. The experiment found that…