One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

A fuzzy controller is usually designed by formulating the knowledge of a human expert into a set of linguistic variables and fuzzy rules. As it is well known, the use of prior knowledge can dramatically improve the performance and quality…

(cont.) which is expected, given their additional knowledge resources. The respondents' urgency in looking for the relevant knowledge is the primary explanation for this difference between the two networks. This difference in knowledge networking among the different groups did not…

This thesis examines the evolution of Internet based knowledge networks (e-knowledge networks) in the domain of sustainable development. The objective of this thesis is to use an engineering systems approach to understand knowledge networks, identify the barriers to their sustainability…

When building Hypermedia/Web Applications, (different) designers are often faced with the same problems over and over again. Those recurring problems soon yield elegant solutions, which can be conveniently described as design patterns. In this paper we present two patterns for…

Evolutionary algorithms (EAs) are merely blind search algorithms, which only make use of the relative fitness of solutions, but completely ignore the nature of the problem. Their performance can be improved by using new multirecombinative approaches, which provide a good…

This study aimed to trace the development of the implementation of knowledge management initiatives in the public sector institutions in Jordan. The study was compared with precedent study had been conducted in 2004. The results showed there is very little…

In this article we describe our experience in the development of a personalizable dissemination model for the Miguel de Cervantes Digital Library’s Web-based newsletter-service, which combines adaptive with adaptable personalization techniques, being capable or ranking news according to navigation-inferred preferences…

An audience driven philosophy for web site design takes the different target audiences as an explicit starting point, and organizes the basic navigation structure accordingly. However, for the designer it is not always easy, or sometimes even impossible, to assess…