One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

(cont.) which is expected, given their additional knowledge resources. The respondents' urgency in looking for the relevant knowledge is the primary explanation for this difference between the two networks. This difference in knowledge networking among the different groups did not…

(cont.) To demonstrate its practical value in large-scale engineering systems, the research applied OPN to two space exploration programs and one aircraft design problem. In our experiments, OPN was able to significantly change the modeling and architectural reasoning process by…

(cont.) In this blurred area, a project/group-based curriculum can be developed to involve casual work areas that can fluctuate in size, based on the specifications of the project. Through the cultivation of this type of environment, the social energies of…

(cont.) characterization, and kink criterion implementation, form a synergistic analysis of the mechanistic debonding behavior affected by moisture. Results have shown that moisture affected debonding is a highly complex phenomenon that involves physical changes in the bond as well as…

by Stephen R. Balzac., Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1987., Title as it appeared in M.I.T. Graduate List, June 1987: An interactive knowledge classifier., Bibliography: leaves 111-112.

The purpose of this research was to generate the knowledge required to design compliant mechanisms that (1) attenuate undesired small-motion angular vibrations in rotational power transmission systems and (2) preserve the desired transmission of large-motion torque/angle inputs. This thesis investigates…

Currently, Draper Laboratory is in the development stages of a gliding autogyro airdrop system. The goal of the project is to design a platform capable of placing small, high value items into urban terrain. Theoretically, autogyros can achieve descent rates…

(cont.) multiple Uninhabited Aerial Vehicles (UAVs) demonstrate that the new DMPC algorithm offers significant computational improvement compared to its centralized counterpart. The controllers developed in this thesis are demonstrated throughout in simulated examples related to vehicle control. Also, some of…