Triazolylmethyl oxazolidinones are novel potent antibacterial agents recently synthesized in our laboratory. PURPOSE. Development of a rapid and specific LC-MS method for evaluating the stability of three potentially active antibacterial triazolylmethyl oxazolidinone compounds, namely PH-27, PH-38 and PH-41, in human…

Globally, privacy is under threat. To many in academia, there is little hope in preserving active domains of seclusion, secrecy or anonymity within an increasingly risk averse, surveillance-networked, global society. Further, scholars within the field of surveillance studies have suggested…

The “Lippmann-Dewey Debate” became widely discussed in the 1980s and 1990s in U.S. media and communication studies, in large part through the influence of James Carey. While Carey’s initial writing on the Lippmann-Dewey exchange was insightful, by 1987, his characterization…

Globally, privacy is under threat. To many in academia, there is little hope in preserving active domains of seclusion, secrecy or anonymity within an increasingly risk averse, surveillance-networked, global society. Further, scholars within the field of surveillance studies have suggested…

The “Lippmann-Dewey Debate” became widely discussed in the 1980s and 1990s in U.S. media and communication studies, in large part through the influence of James Carey. While Carey’s initial writing on the Lippmann-Dewey exchange was insightful, by 1987, his characterization…

When presidents attempt to transform a country, they do so by utilizing a keen understanding of the status quo and a knowledge of how to challenge it—and most often, they challenge it by performing a key speech. Within this speech,…

Metabolomics is a relatively new high-throughput technology that aims at measuring all endogenous metabolites within a biological sample in an unbiased fashion. The resulting metabolic profiles may be regarded as functional signatures of the physiological state, and have been shown…

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Polyketides are an important group of secondary metabolites, many of which have important industrial applications, including in the food and pharmaceutical industries. Polyketides are synthesized from one of three classes of enzymes differentiated by their biochemical features and product structure:…

The US Food and Drug Administration (FDA) has recently suggested that the bioequivalence (BE) for products of drugs with narrow therapeutic indices (NTI) be assessed by the approach of reference-scaled average BE (SABE). Subsequently, in December, 2012, the FDA issued…