The Knowledge Engineering Suite is an ontology production method, based on relationship networks, for knowledge representation inside specific contexts. The production of these ontologies has three basic steps, since catching the client data, knowledge base creation, and information retrieval and…

One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

It is interesting and important to compare, analyze and assess the alternative tools that could be used in the area of Knowledge Representation. In this paper we present a reasearch line associated to this goal: to formally establish the relation…

(cont.) as well, firms have an incentive to require coordinated investments in technology across the enterprise. Still, research in IS has also highlighted the fact that the productivity of computer investments is highly dependent on co-investment in complementary assets (for…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

This thesis analyzes how the Auto-ID technology and information infrastructure will change the management and distribution of pharmaceutical products within the health care industry by enabling item level product traceability functionality. The complexity of the health care industry is steadily…

This paper proposes an original generic hierarchical framework in order to facilitate the modeling stage of complex autonomous robotics mission planning problems with action uncertainties. Such stochastic planning problems can be modeled as Markov Decision Processes [5]. This work is…

Given an instance of an optimization problem together with an optimal solution, we consider the scenario in which this instance is modified locally. In graph problems, e. g., a singular edge might be removed or added, or an edge weight…

Background: Local adaptation of guidelines may increase compliance with guidelines that have been developed at a national level and are often not used in practice because of contextual factors. We have developed a representation scheme known as HieroGLIF, that facilitates…

Firm boundaries have been the subject of much scholarly interest in recent years, as firms increasingly hire external, "contingent" workers and outsource previously core activities. However, little empirical research has directly studied what happens differently inside the firm's boundaries, versus…