In this article we study the retrospective inverse problem. The retrospective inverse problem consists of in the reconstruction of a priori unknown initial condition of the dynamic system from its known final condition. Existence and uniqueness of the solution is…

Research studying effective planning and optimization in the vehicle routing field has increased tremendously in the last few decades. Advances in technology and computational power have encouraged researchers to consider various vehicle routing problem types and constraints, and to experiment…

One does not have to be a fierce advocate of dialectics to consider the claim that the exercise of dystopic imagination may represent a necessary stage to think a better world. If it is good to know the worst, that does not…

One does not have to be a fierce advocate of dialectics to consider the claim that the exercise of dystopic imagination may represent a necessary stage to think a better world. If it is good to know the worst, that does not…

One does not have to be a fierce advocate of dialectics to consider the claim that the exercise of dystopic imagination may represent a necessary stage to think a better world. If it is good to know the worst, that does not…

Market failures in human capital investment and innovation explain the main features of human development and economic growth. This is shown in a Schumpeterian multi-country model with technology transfer and trade. Thus, only institutions expanding investments in nutrition, education, health,…

Detailed knowledge of the tip apex structure is necessary for quantitative comparison between theory-based simulations and experimental observations of tip-substrate interactions in scanning probe microscopy (SPM). Here, we discuss field ion microscopy (FIM) techniques to characterize and atomically define SPM…

La separación de biomoléculas de alto valor añadido, con tamaño y características similares como la albúmina de suero bovino (BSA) y la lactoferrina (LF), representa uno de los retos más difíciles en la industria bioquímica. Durante 100 años las técnicas…

Breast Cancer Resistance Protein (BCRP, ABCG2) and P-glycoprotein (P-gp, ABCB1, MDR1) are
members of the G and B subfamily of the ATP-binding cassette (ABC) efflux transporters, respectively.
Both transporters use the energy of ATP hydrolysis for substrate efflux.…

En esta tesis doctoral se propone la utilización de una metodología espacial para la integración de construcciones rurales en su entorno, mediante la utilización de un sistema de evaluación de criterios múltiples (ECM), en un entorno web asistido por la…