Understanding the biological signals encoded in a genome is a key challenge of computational biology. These signals are encoded in the four-nucleotide alphabet of DNA and are responsible for all molecular processes in the cell. In particular, the genome contains…

This thesis explores how doctors and nurses use documents to share their knowledge within and across healthcare settings. In addressing this question I draw on a 15-month, multi-sited ethnographic study in several pediatric health care settings, following patients from primary…

In this work we present an approach to model an action-oriented system controlled by BDI agents using a defeasible argumentation formalism to represent its knowledge. Here, our main concern will be modelling the software agents that drive the physical robots.

Early years professionals wrote about changes in their settings as part of their MA studies, and reflected on the use of theories of leadership in implementing these changes. This article describes a documentary analysis of the scripts produced. Initially basing…

The shift towards global networking brings with it many opportunities and challenges. In this paper, we discuss key technologies in achieving global semantic interoperability among heterogeneous information systems, including both traditional and web data sources. In particular, we focus on…

Most unsupervised indigenous knowledge (IK) are known to be very useful in combating critical health issues as well as being dangerous if the administration is abused. Despite the fact that these locally prepared herbal medicine are not encouraged to be…

This paper investigates the potential for a carbon tax to induce R&D, and for the consequent induced technical change (ITC) to lower the macroeconomic cost of abating carbon emissions. ITC is modelled within a general equilibrium simulation of the U.S.…

This thesis will explore the design and optimization of a peer-to-peer network application as a solution to complex content management problems. Currently, most content management systems are expensive, cumbersome and inflexible custom solutions that require knowledge workers to change their…

Effective document retrieval using domain knowledge and semantics is one of the major challenges in Information Retrieval. Over the last years, there has been a growing interest in ontologies as an artifact for human knowledge representation and a critical component…

Knowledge of how groups of people interact is important in many disciplines, e.g. organizational behavior, social network analysis, knowledge management and ubiquitous computing. Existing studies of social network interactions have either been restricted to online communities, where unambiguous measurements about…