by Stephen R. Balzac., Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1987., Title as it appeared in M.I.T. Graduate List, June 1987: An interactive knowledge classifier., Bibliography: leaves 111-112.

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

This thesis presents research about the potential business impacts of the Semantic Web. The concept of the Semantic Web is an expansion of the Web for computers, enabling them to comprehend the meaning of information. In addition, Semantic Web Services…

This thesis proposes a miethodology for the design of man-machine interfaces by combining top-down and bottom-up processes in vision. From a computational perspective, we propose that the scientific-cognitive question of combining top-down and bottom-up knowledge is similar to the engineering…

Continued advances in the semiconductor industry will require the introduction of new materials and processes concurrent with shrinking device dimensions. These simultaneous demands drastically reduce margins for error and necessitate an increasingly quantitative understanding of semiconductor processes. Leaders of the…

This dissertation investigates how rapid learning occurs in high technology industries, many of which operate in what Bourgeois and Eisenhardt (1988) term "high velocity environments." The dissertation consists of three empirical studies, which follow the method of extended case study…

Building energy simulation (ES) and computational fluid dynamics (CFD) can play important roles in building design by providing essential information to help design energy-efficient, thermally comfortable and healthy buildings. However, separate applications of ES and CFD usually cannot give an…

Background: Local adaptation of guidelines may increase compliance with guidelines that have been developed at a national level and are often not used in practice because of contextual factors. We have developed a representation scheme known as HieroGLIF, that facilitates…

(cont.) which are then applied to developmentally acquire new object representations. The humanoid robot therefore sees the world through the caregiver's eyes. Building an artificial humanoid robot's brain, even at an infant's cognitive level, has been a long quest which…

Modem society requires reliable and safe operation of its infrastructure. Policymakers believe that, in many industries, competitive markets and regulatory incentives will result in system performance superior to that under command-and-control regulation. Analytical techniques to evaluate the reliability and safety…