by Gregory K. Clancey., Thesis (Ph.D.)--Massachusetts Institute of Technology, Program in Science, Technology and Society, 1999., Includes bibliographical references.

(cont.) with recombinant material. The in vitro system established in this study will facilitate the investigation of platinum-DNA damage by DNA repair processes and help elucidate the role of specific post-translational modification in NER of platinum-DNA adducts at the physiologically…

This thesis examines the evolution of Internet based knowledge networks (e-knowledge networks) in the domain of sustainable development. The objective of this thesis is to use an engineering systems approach to understand knowledge networks, identify the barriers to their sustainability…

Knowledge networks have received a significant amount of attention in the past few decades as people look beyond corporate governance and resource-based approaches to uncover sources of competitive advantage. While this area of research is useful for organizations in general,…

If we are to understand how we can build machines capable of broad purpose learning and reasoning, we must first aim to build systems that can represent, acquire, and reason about the kinds of commonsense knowledge that we humans have…

This thesis is based on the premise that small nations face unique challenges in the quest for economic prosperity. They have a small domestic economy and are more dependent than larger economies on international trade. Smallness typically entails a lack…

The state of business in the U.S. automobile industry is such that competition is fierce, and consumers have a perplexing number of alternatives from which to choose. The final purchase decision by the consumer is where most industry experts focus…

In recent years we have seen a confluence of science and technology that portends great impact to business strategy and product development. Just as physicists, chemists and biologists have extended their knowledge to other fields in pursuit of their own…

The collaboration of researchers in different fields, institutions, and nations continues to be important as new ideas and solutions result from the combination of different knowledge and experiences. The Cambridge MIT Institute (CMI) Online Project Assessment System(OPAS) aims to collect…

There is a great need among educators for a way to quickly assign teams in large or distance learning classrooms in a manner superior to random assignment or student self-selection. Forming teams based on knowledge of students' characteristics is too…