Policies to avert the threat of dangerous climate change focus on stabilizing atmospheric carbon dioxide concentrations by drastically reducing anthropogenic emissions of carbon. Such reductions require limiting the use of fossil fuels-which supply the bulk of energy to economic activity,…

We strain our eyes, cramp our necks, and destroy our hands trying to interact with computer on their terms. At the extreme, we strap on devices and weigh ourselves down with cables trying to re-create a sense of place inside…

The thesis comprises three essays on various aspects of the development and diffusion of pharmaceutical innovations, woven together by the idea that the production of clinical knowl- edge influences organizational design, pricing, and advertising decisions in the pharmaceutical industry -…

Integration of daylight availability in time and architectural space is a critical element in achieving optimal comfort and productivity, as well as in minimizing energy consumption. In recent years, there has been an increase in the demand of the better…

A multiobjective, multidisciplinary design optimization methodology for mathematically modeling the distributed satellite system (DSS) conceptual design problem as an optimization problem has been developed to advance the state-of-the-art in complex distributed satellite network design. An increasing number of space missions…

One important purpose for creating clinical practice guidelines is to improve quality of care by reducing variations in practice. In the current healthcare environment, guidelines are being advocated as a means to disseminate research findings, standardize care, improve quality of…

El presente artículo expone la línea de trabajo de algunos de los integrantes del Grupo de Investigación en Informática de Gestión, quienes han desarrollado una serie de herramientas para la Gestión del Conocimiento, tanto en entidades públicas como privadas. Las…

(cont.) as well, firms have an incentive to require coordinated investments in technology across the enterprise. Still, research in IS has also highlighted the fact that the productivity of computer investments is highly dependent on co-investment in complementary assets (for…

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

This thesis analyzes how the Auto-ID technology and information infrastructure will change the management and distribution of pharmaceutical products within the health care industry by enabling item level product traceability functionality. The complexity of the health care industry is steadily…