This thesis will explore the design and optimization of a peer-to-peer network application as a solution to complex content management problems. Currently, most content management systems are expensive, cumbersome and inflexible custom solutions that require knowledge workers to change their…

Knowledge of how groups of people interact is important in many disciplines, e.g. organizational behavior, social network analysis, knowledge management and ubiquitous computing. Existing studies of social network interactions have either been restricted to online communities, where unambiguous measurements about…

Understanding the biological signals encoded in a genome is a key challenge of computational biology. These signals are encoded in the four-nucleotide alphabet of DNA and are responsible for all molecular processes in the cell. In particular, the genome contains…

This thesis explores how doctors and nurses use documents to share their knowledge within and across healthcare settings. In addressing this question I draw on a 15-month, multi-sited ethnographic study in several pediatric health care settings, following patients from primary…

Heavily used in the manufacture of integrated circuits, chemical-mechanical polishing (CMP) is becoming an enabling technology for microelectromechanical systems (MEMS). To reliably use CMP in the manufacturing process, designers must be able to accurately predict the CMP process and control…

Nature and Gnosticism are problematic terms. With the discovery of a library of so called heretical Gnostic texts in 1945, theologians, historians, and believers the world over have been exposed to Christian texts that call into question the liturgical lineage…

The thesis comprises three essays on various aspects of the development and diffusion of pharmaceutical innovations, woven together by the idea that the production of clinical knowl- edge influences organizational design, pricing, and advertising decisions in the pharmaceutical industry -…

To take further steps along the path toward true artificial intelligence, systems must be built that are capable of learning about the world around them through observation and explanation. These systems should be flexible and robust in the style of…

Corporate household (CHH) refers to the organizational information about the structure within the corporation and
a variety of inter-organizational relationships. Knowledge derived from this data is becoming increasingly important
for improving data quality in applications, such as Customer…

This study offers a detailed case study of how Toyota facilitates interorganizational knowledge transfers among within its production network. In particular, we identiify and examine six key institutionalized knowledge sharing routines developed by Toyota and its suppliers. By examining how…