(cont.) and (2) a forward approach which achieves optimality at the start and grows the system using an optimization technique. We systematically compare the two staging techniques in the context of telescope arrays and evaluate the hypothesis that the backward…

There exists a large amount of knowledge representation models. But most of them have significant limitations at the epistemic level. They do not have explanatory power. Most of them do not have means to represent some functional needs to work…

by Yaichi Aoshima., Thesis (Ph. D.)--Massachusetts Institute of Technology, Sloan School of Management, 1996., Includes bibliographical references (p. 253-264).

by Roberta M. Braum., Thesis (S.M.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1999., Includes bibliographical references (p. 57).

The decline in Pharmaceutical R&D productivity has been attributed to high clinical failure rates suggesting that targets, leads and clinical candidates may be of lower quality in recent years. Senior R&D management generally believes that a greater integration of drug…

Chapter one is titled "Social Capital and Group Banking." Lending to the poor is costly due to high screening, monitoring, and enforcement costs. Group lending advocates believe individuals are able to select creditworthy peers, monitor the use of loan proceeds,…

This thesis presents research about the potential business impacts of the Semantic Web. The concept of the Semantic Web is an expansion of the Web for computers, enabling them to comprehend the meaning of information. In addition, Semantic Web Services…

This thesis proposes a miethodology for the design of man-machine interfaces by combining top-down and bottom-up processes in vision. From a computational perspective, we propose that the scientific-cognitive question of combining top-down and bottom-up knowledge is similar to the engineering…

Building energy simulation (ES) and computational fluid dynamics (CFD) can play important roles in building design by providing essential information to help design energy-efficient, thermally comfortable and healthy buildings. However, separate applications of ES and CFD usually cannot give an…

Background: Local adaptation of guidelines may increase compliance with guidelines that have been developed at a national level and are often not used in practice because of contextual factors. We have developed a representation scheme known as HieroGLIF, that facilitates…