Les propriétés pharmacocinétiques d’un nouveau médicament et les risques d’interactions médicamenteuses doivent être investigués très tôt dans le processus de recherche et développement. L’objectif principal de cette thèse était de concevoir des approches prédictives de modélisation du devenir du médicament…

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It was hypothesized that children with physical disabilities would show a deficit in procedural and declarative knowledge of ball catching compared to age-matched non-disabled children. The first group of children consisted of sixteen children with physical disabilities, three girls and…

The high rate of sexually transmitted diseases and teen pregnancies among the Cree adolescents indicate that this population frequently engages in unprotected sexual activities. AIDS is a critical health problem worldwide and AIDS contamination within a Cree community could be…

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The main objective of the present work is to investigate the nature of the cognitive processes responsible for the problem-solving operations of novices, intermediates, and experts in a semantically rich and complex domain, i.e. electronics trouble shooting, in relation to…

Knowledge management in organizations, the learning objects paradigm, the advent of a new web generation, and the “Semantic Web” are major actual trends that reveal a potential for a renewed distance learning pedagogy. First and foremost is the use of…

Au Canada et au Québec, au cours des années 2000, la migration des travailleurs qualifiés originaires d’Amérique du Sud a connu une croissance très rapide. Pourtant, ce flux migratoire et sa composante féminine ne semblent pas avoir fait l’objet d’une…

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The thesis examines aspects of the construction of methylmercury as an authoritative object of knowledge for Chisasibi, a Cree community on the James Bay coast in northern Quebec. I describe the evolution of a particular set of spheres of exchange…