This paper presents a proposal for an architecture that integrates knowledge discovery systems (automatic acquisition) and knowledge based systems (experts systems). This work formulates considerations over the viability of the implementation of this architecture according to the advance of the…

Se evaluó el nivel de conocimiento y desempeño de Buenas Practicas Clínicas de los investigadores participantes en ensayos clínicos en ejecución en 5 centros asistenciales, desde febrero a abril de
2006. El nivel de conocimiento se evaluó mediante una encuesta,…

The paper presents a formal model for a knowledge repository shared by members of a Virtual Community of Practice (VCPs), describes how the repository can be used to underpin collaborative problem solving, and how to build computer support for such…

This article presents a procedure for constructing a taxonomy of COTS products in the field of Requirements Engineering (RE). The taxonomy and the obtained information reach transcendental benefits to the selection of systems and tools that aid to RE-related actors…

This paper presents a neuro-fuzzy network where all its parameters can be tuned simultaneously using Genetic Algorithms. The approach combines the merits of fuzzy logic theory, neural networks and genetic algorithms. The proposed neuro-fuzzy network does not require a priori…

Complex control tasks may be solved by dividing them into a more specific and more easily handled subtasks hierarchy. Several authors have demonstrated that the incremental layered evolution paradigm allows obtaining controllers capable of solving this type of tasks. In…

This work is focussed on the development and analysis of a new class of algorithms, called cellular memetic algorithms (cMAs), which will be evaluated here on the satisfiability problem (SAT). For describing a cMA, we study the effects of adding…

In the design of activities for Web-Based Education Systems, the concept of Didactic Object or Learning Object, has appeared as the axis of a new paradigm concerned with the reusability of contents and activities, due to its organization from a…

Son diversas las etapas que deben cumplimentarse en Cuba para la introducción de un nuevo
medicamento en el mercado, dentro de las que se encuentran la evaluación de parámetros físico-químicos,
farmacológicos, toxicológicos y clínicos. Los organismos competentes a nivel nacional…

En la presente revisión bibliográfica se esbozan los principales diseños de experimentos que encuentran aplicación en el campo de la tecnología y control de los medicamentos. Se muestran ejemplos de la literatura especializada donde se evidencian las posibilidades que brindan…