| Título: | SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF OXIME ESTERS FROM DIHYDROCUMIC ACID |
| Autores: |
Gao, Yanqing Song, Jie Shang, Shibin Wang, Dan Li, Jian |
| Fecha: | 2012-05-02 |
| Publicador: | Bioresources |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| Tema: | β-pinene; Dihydrocumic acid; Oxime esters; Antibacterial activity |
| Descripción: | Dihydrocumic acid was prepared from β-pinene through oxidation and dehydration. Then, ten oxime esters from dihydrocumic acid were synthesized. Reaction conditions of the oxime esters were adjusted and their structures were characterized by IR, 1H-NMR, MS, and elemental analysis. The antibacterial activity of these newly synthesized oxime esters against Gram-negative bacteria and Gram-positive bacteria was also investigated using the inhibition zone method. The preliminary results indicated that seven compounds displayed better antibacterial activity against Gram-negative bacteria compared with bromogeramine, a commercially available antibacterial agent. |
| Idioma: | Inglés |